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Genentech takes the health and safety of our patients, customers, employees and local communities very seriously, and we are actively responding to the global COVID-19 pandemic. For more, please visit our COVID-19 response page.

Focus on Metabolism

Genentech is committed to discovering and developing innovative medicines for metabolic diseases. We focus on creating new treatment options for patients with diabetes to manage their disease and avoid its complications.

While new medications for glucose control have been developed in recent years, none of the available medications affects the steady deterioration in pancreatic function that is characteristic of type 2 diabetes. The loss of physiologic glucose control as pancreatic function declines mean that diabetic retinopathy and nephropathy are significant and growing health problems that we seek to address.

Key Publications

PLoS One, February 2013
Antibody-Mediated Activation of FGFR1 Induces FGF23 Production and Hypophosphatemia
Science Translational Medicine, December 2011
Amelioration of Type 2 Diabetes by Antibody-Mediated Activation of Fibroblast Growth Factor Receptor 1
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