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Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 1 - 50 OF 12506 RESULTS

Murine double minute 2 inhibition alone or with cytarabine in acute myeloid leukemia: Results from an idasanutlin phase 1/1b study?
Leukemia Research, ISSN: 01452126
Karen Yee; Cristina Papayannidis; Norbert Vey; Michael J. Dickinson; Kevin Kelly; Sarit E. Assouline; Margaret Kasner; Karen Seiter; Mark W. Drummond; Sung-Soo Yoon; Je-Hwan Lee; Steven Blotner; Lori Jukofsky; William E. Pierceall; Jianguo Zhi; Silke Simon; Brian Higgins; Gwen L. Nichols; Annabelle Monnet; Susanne Muehlbauer; Marion Ott; Lin-Chi Chen; Giovanni Martinelli
Curse or Cure? A Perspective on the Developability of Aldehydes as Active Pharmaceutical Ingredients
Journal of Medicinal Chemistry,
Christian Gampe; Vishal Verma
Accurate assembly of the olive baboon (Papio anubis) genome using long-read and Hi-C data
GigaScience,
Sanjit Singh Batra; Michal Levy-Sakin; Jacqueline Robinson; Joe Guillory; Steffen Durinck; Tauras P. Vilgalys; Pui-Yan Kwok; Laura A. Cox; Somasekar Seshagiri; Yun S. Song; Jeffrey D. Wall
Venetoclax-rituximab with or without bendamustine vs bendamustine-rituximab in relapsed/refractory follicular lymphoma
Blood,
Pier Luigi Zinzani; Ian Flinn; Sam L S Yuen; Max S. Topp; Chiara Rusconi; Isabelle Fleury; Le D?; Christopher Arthur; Barbara Pro; Giuseppe Gritti; Michael Crump; Adam M. Petrich; Divya Samineni; Arijit Sinha; Elizabeth Punnoose; Edith Szafer-Glusman; Nathalie Spielewoy; Mehrdad Mobasher; Kathryn Humphrey; Martin Kornacker; Wolfgang Hiddemann
Nature Communications, ISSN: 20411723
Akhilesh Pandey; Eric Stawiski; Steffen Durinck; Harsha Gowda; Leonard Goldstein; Mustafa A. Barbhuiya; Markus S. Schr?der; Sreelakshmi K. Sreenivasamurthy; Sun-Whe Kim; Sameer Phalke; Kushal Suryamohan; Kayla Lee; Papia Chakraborty; Vasumathi Kode; Xiaoshan Shi; Aditi Chatterjee; Keshava Datta; Aafaque A. Khan; Tejaswini Subbannayya; Jing Wang; Subhra Chaudhuri; Sanjiv Gupta; Braj Raj Shrivastav; Bijay Jaiswal; Satish S. Poojary; Shushruta Bhunia; Patricia Garcia; Carolina Bizama; Lorena Rosa; Wooil Kwon; Hongbeom Kim; Youngmin Han; Thakur Deen Yadav; Vedam Laxmi Ramprasad; Amitabha Chaudhuri; Zora Modrusan; Juan Carlos Roa; Pramod Kumar Tiwari; Jin-Young Jang; Somasekar Seshagiri
Mitigating the risk of cytokine release syndrome in a Phase I trial of CD20/CD3 bispecific antibody mosunetuzumab in NHL: impact of translational system modeling
npj Systems Biology and Applications,
Iraj Hosseini; Kapil Gadkar; Eric Stefanich; Chi-Chung Li; Laura Sun; Yu-Waye Chu; Saroja Ramanujan
Journal of Patient-Reported Outcomes, ISSN: 25098020
Rachael Lawrance; Evgeny Degtyarev; Philip Griffiths; Peter Trask; Helen Lau; Denise D’Alessio; Ingolf Griebsch; Gudrun Wallenstein; Kim Cocks; Kaspar Rufibach
Single-Cell Reconstruction of Human Basal Cell Diversity in Normal and Idiopathic Pulmonary Fibrosis Lungs
American Journal of Respiratory and Critical Care Medicine,
Gianni Carraro; Apoorva Mulay; Changfu Yao; Takako Mizuno; Bindu Konda; Martin Petrov; Daniel Lafkas; Joe Arron; Cory M. Hogaboam; Peter Chen; Dianhua Jiang; Paul W. Noble; Scott H. Randell; Jonathan L. McQualter; Barry R. Stripp
Scientific Reports, ISSN: 20452322
Rebecca M. Reese; Michelle Dourado; Keith Anderson; Soren Warming; Kimberly L. Stark; Alessia Balestrini; Eric Suto; Wyne Lee; Lorena Riol Blanco; Shannon Shields; David Hackos
Nature Communications, ISSN: 20411723
Kelvin F. Cho; Taylur Ma; Christopher M. Rose; Donald S. Kirkpatrick; Kebing Yu; Robert Blake
Activation of the IRE1 RNase through remodeling of the kinase front pocket by ATP-competitive ligands
Nature Communications,
Elena Ferri; Adrien Le Thomas; Heidi Ackerly Wallweber; Eric S. Day; Ben Walters; Susan Kaufman; Marie-Gabrielle Braun; Kevin Clark; Maureen Beresini; Kyle Mortara; Yung-Chia Ariel Chen; Breanna Canter; Wilson Phung; Peter Liu; Alfred Lammens; Avi Ashkenazi; Joachim Rudolph; Weiru Wang
Bivalent antibody pliers inhibit β-tryptase by an allosteric mechanism dependent on the IgG hinge
Nature Communications,
Henry Maun; Rajesh Vij; Ben Walters; Ashley Morando; Janet Jackman; Ping Wu; Alberto Estevez; Xiaocheng Chen; Yvonne Franke; Terry Lipari; Mark Dennis; Daniel Kirchhofer; Claudio Ciferri; Kelly Loyet; Tangsheng Yi; Charles Eigenbrot; Bob Lazarus; JT Koerber
Calibrating the in vitro–in vivo correlation for OATP-mediated drug-drug interactions with rosuvastatin using static and PBPK models
Drug Metabolism and Disposition, ISSN: 00909556
Rucha Sane; Kit Wun Kathy Cheung; Péter Kovács; Taleah Farasyn; Ruina Li; Annamaria Bui; Luna Musib; Emese Kis; Emile Plise; Zsuzsanna Gáborik
The role of polygenic risk and susceptibility genes in breast cancer over the course of life
Nature Communications,
Nina Mars; Elisabeth Widén; Sini Kerminen; Tuomo Meretoja; Matti Pirinen; Priit Palta; Aki S. Havulinna; Amanda Elliott; Anastasia Shcherban; Andrea Ganna; Anu Jalanko; Arto Lehisto; Elina Kilpel?inen; Georg Brein; Ghazal Awaisa; Hannele Laivuori; Henrike Heyne; Jarmo Harju; Jiwoo Lee; Juha Karjalainen; Jukka T. Koskela; Kalle P?rn; Kati Donner; Kristin Tsuo; Manuel González Jiménez; Mari Kaunisto; Mari E. Niemi; Mary Pat Reeve; Mervi Aavikko; Mitja Kurki; Oluwaseun A. Dada; Pietro della Briotta Parolo; Risto Kajanne; Sina Rüeger; Susanna Lemmel?; Taru Tukiainen; Tiinamaija Tuomi; Timo P. Sipil?; Tuomo T. J. Kiiskinen; Vincent Llorens; Adam Ziemann; Anne Lehtonen; Apinya Lertratanakul; Bob Georgantas; Bridget Riley-Gillis; Danjuma Quarless; Fedik Rahimov; Howard Jacob; Jeffrey Waring; Justin Wade Davis; Nizar Smaoui; Relja Popovic; Sahar Esmaeeli; Athena Matakidou; Ben Challis; David Close; Eleonor Wigmore; Slavé Petrovski; Chia-Yen Chen; Ellen Tsai; Heiko Runz; Jimmy Liu; Paola Bronson; Sally John;
Scientific Reports, ISSN: 20452322
Yuanyuan Wang; Meghan Kerrisk Campbell; Irene Tom; Oded Foreman; Jesse E. Hanson; Morgan Sheng
Functional characterization of SMARCA4 variants identified by targeted exome-sequencing of 131,668 cancer patients
Nature Communications,
Tharu M. Fernando; Robert Piskol; Russell Bainer; Ethan S. Sokol; Sally E. Trabucco; Qing Zhang; Huong Trinh; Sophia L. Maund; Marc Kschonsak; Subhra Chaudhuri; Zora Modrusan; Tom Januario; Bob Yauch
Integrated digital pathology and transcriptome analysis identifies molecular mediators of T-cell exclusion in ovarian cancer
Nature Communications,
Mélanie Desbois; Akshata R. Udyavar; Lisa Ryner; Cleopatra Kozlowski; Ying Guan; Milena Dürrbaum; Shan Lu; Jean-Philippe Fortin; Hartmut Koeppen; James Ziai; Ching-Wei Chang; Shilpa Keerthivasan; Marie Plante; Richard Bourgon; Carlos Bais; Priti Hegde; Anneleen Daemen; Shannon Turley; Wang
Advances in Therapy, ISSN: 18658652 0741238X
Jennie Best; Shalini V. Mohan; Amanda M. Kong; Krish Patel; John M. Pagel; Boris Ivanov; Otis W. Brawley; Krutika Jariwala-Parikh; James Zazzali; John Pauk
Scientific Reports, ISSN: 20452322
Sara Dominguez; Timothy K. Earr; Michelle Dourado; Hai Ngu; Bill Meilandt; Jesse E. Hanson
Application of a risk-management framework for integration of stromal tumor-infiltrating lymphocytes in clinical trials
npj Breast Cancer,
Jan Hude?ek; Leonie Voorwerk; Maartje Van Seijen; Iris Nederlof; Michiel de Maaker; Jose van den Berg; Koen Van De Vijver; Karolina Sikorska; Sylvia Adams; Sandra Demaria; Viale; Torsten Nielsen; Sunil Badve; Stefan Michiels; W Fraser Symmans; Christos Sotiriou; David Rimm; Stephen M. Hewitt; Carsten Denkert; Sibylle Loibl; Sherene Loi; John M. S. Bartlett; Giancarlo Pruneri; Deborah A. Dillon; Maggie Chon U. Cheang; Andrew Tutt; Jacqueline A. Hall; Zuzana Kos; Roberto Salgado; Kok; Hugo M. Horlings; Aini Hyyti?inen; Akira I. Hida; Alastair Thompson; Alex Lefevre; Alexander J. Lazar; Allen Gown; Amy Lo; Anna Sapino; Anant Madabhushi; Andre Moreira; Andrea Richardson; Andrea Vingiani; Andrew H. Beck; Andrew M. Bellizzi; A. Steven Guerrero; Anita Grigoriadis; Anna Ehinger; Ana C. Garrido-Castro; Anne Vincent-Salomon; Anne-Vibeke Laenkholm; Ashish Sharma; Ashley Cimino-Mathews; Ashok Srinivasan; Balazs Acs; Baljit Singh; Benjamin Calhoun; Benjamin Haibe-Kans; Benjamin Solomon; Bibhusal Thapa; Brad H. Nelson;
Communications Biology, ISSN: 23993642
Kannan Sankar; Kam Hon Hoi; Isidro Hotzel
Nature Communications, ISSN: 20411723
Keren Bahar Halpern; Hassan Massalha; Rachel K. Zwick; Andreas E. Moor; David Castillo-Azofeifa; Milena Rozenberg; Lydia Farack; Adi Egozi; Dan R. Miller; Inna Averbukh; Yotam Harnik; Noa Weinberg-Corem; Frederic De Sauvage; Ido Amit; Ophir D. Klein; Michal Shoshkes-Carmel; Shalev Itzkovitz
Pitfalls in assessing stromal tumor infiltrating lymphocytes (sTILs) in breast cancer
npj Breast Cancer,
Zuzana Kos; Elvire Roblin; Rim S. Kim; Stefan Michiels; Brandon D. Gallas; Weijie Chen; Koen Van De Vijver; Shom Goel; Sylvia Adams; Sandra Demaria; Viale; Torsten Nielsen; Sunil Badve; W Fraser Symmans; Christos Sotiriou; David Rimm; Stephen M. Hewitt; Carsten Denkert; Sibylle Loibl; Stephen J Luen; John M. S. Bartlett; Peter Savas; Giancarlo Pruneri; Deborah A. Dillon; Maggie Chon U. Cheang; Andrew Tutt; Jacqueline A. Hall; Kok; Hugo M. Horlings; Anant Madabhushi; Jeroen van der Laak; Francesco Ciompi; Anne-Vibeke Laenkholm; Enrique Bellolio; Tina Gruosso; Stephen B. Fox; Juan Carlos Araya; Giuseppe Floris; Jan Hude?ek; Leonie Voorwerk; Andrew H. Beck; Jen Kerner; Denis Larsimont; Sabine Declercq; Gert G.G.M. Van Den Eynden; Pusztai; Anna Ehinger; Wentao Yang; Khalid AbdulJabbar; Yinyin Yuan; Rajendra Singh; Crispin Hiley; Maise al Bakir; Alexander J. Lazar; Stephen Naber; Stephan Wienert; Miluska Castillo; Giuseppe Curigliano; Maria V. Dieci; Fabrice Andre; Charles Swanton; Jorge S. Reis-Filho; Joseph
Nature Communications, ISSN: 20411723
Aswini Krishnan; Jean Berthelet; Emilie Renaud; Sebastian Rosigkeit; Ute Distler; Eric Stawiski; Jing Wang; Zora Modrusan; Marc Fiedler; Mariann Bienz; Stefan Tenzer; Arno Schad; Wilfried Roth; Bernd Thiede; Somasekar Seshagiri; Thomas J. Musholt; Krishnaraj Rajalingam
Drug Metabolism and Disposition, ISSN: 1521009X
Victor Yip; Isabel Figueroa; Brandon Latifi; Shab Masih; Carl Ng; Douglas Leipold; Amrita Kamath; Ben-Quan Shen
Application of a Two-Analyte Integrated Population Pharmacokinetic Model to Evaluate the Impact of Intrinsic and Extrinsic Factors on the Pharmacokinetics of Polatuzumab Vedotin in Patients with Non-Hodgkin Lymphoma
Pharmaceutical Research, ISSN: 07248741
Dan Lu; Tong Lu; Rong Shi; Leonid Gibiansky; Priya Agarwal; Colby S. Shemesh; Randy Dere; Uzor Ogbu; Jamie Hirata; Pascal Chanu; Sandhya Girish; Jin Yan Jin; Chunze Li; Dale Miles
Development of an anti-drug antibody assay to detect anti-drug antibodies?to protein and PEG?in a PEGylated molecule
Bioanalysis,
Yanqiu Liu; Nancy Yu; Mehraban Khosraviani; Eric Wakshull
Communications Biology, ISSN: 23993642
Andrew Ah Young; Sterling C. Eckard; Alvin Gogineni; Hongkang Xi; S. Jack Lin; Gerhardy; Christian Cox; Qui T. Phung; Jason Hackney; Anand Kumar Katakam; Mike Reichelt; Patrick Caplazi; Paolo Manzanillo; Juan Zhang; Meron Roose-Girma; Lucinda W. Tam; Robert J (Research) Newman; Aditya Murthy; Robby Weimer; Jennie Lill; Wyne P. Lee; Michele Grimbaldeston; Daniel Kirchhofer; Menno van Lookeren Campagne
Pan-cancer population pharmacokinetics and exposure-safety and -efficacy analyses of atezolizumab in patients with high tumor mutational burden
Pharmacology Research and Perspectives,
Colby S. Shemesh; Phyllis Chan; Fatema A. Legrand; David Shames; Meghna Das Thakur; Jane Shi; Lorna Bailey; Shweta Vadhavkar; Xian He; Wei Zhang; Rene A. Bruno
Phenotypic expression and clinical outcomes in a South Asian PRKAG2 cardiomyopathy cohort
Scientific Reports,
Hisham Ahamed; Aniketh Vijay Balegadde; Shilpa Menon; Ramesh Menon; Aishwarya Ramachandran; Navin Mathew; Natarajan; Indu Ramachandran Nair; Rajesh Kannan; Meghna Shankar; Oommen K. Mathew; Thong Tom Nguyen; Ravi Gupta; Eric Stawiski; Vedam Laxmi Ramprasad; Somasekar Seshagiri; Sameer Phalke
Venetoclax Plus Rituximab in Relapsed Chronic Lymphocytic Leukemia: 4-Year Results and Evaluation of Impact of Genomic Complexity and Gene Mutations From the MURANO Phase III Study
Journal of Clinical Oncology,
Kater; Jenny Wu; Thomas J. Kipps; Barbara Eichhorst; Hillmen; D&#39;Rozario; Sarit E. Assouline; Carolyn J. Owen; Tadeusz Robak; Javier De La Serna; Jaeger; Guillaume Cartron; Marco Montillo; Julie Dubois; Eric Eldering; Clemens H. Mellink; Anne-Marie Van Der Kevie-Kersemaekers; Su Young Kim; Brenda Chyla; Elizabeth Punnoose; Chris Bolen; Zoe June Assaf; Yanwen Jiang; Jue Wang; Marcus Lefebure; Michelle Boyer; Kathryn Humphrey; John F. Seymour
Nature Reviews Drug Discovery, ISSN: 14741784 14741776
Amanda R. Moore; Scott C. Rosenberg; Frank McCormick; Shiva Malek
Targeting Autophagy to Treat Cancer: Challenges and Opportunities
Frontiers in Pharmacology,
Junghyun Lim; Aditya Murthy
Practical Early Development Synthesis of Nav17 Inhibitor GDC-0310
Synthesis (Germany), ISSN: 00397881
Andy Stumpf; Frederic St-Jean; David Lao; Zhiyong (Jay) Cheng; Remy Angelaud; Francis Gosselin
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 10916490 00278424
Amos Baruch; Chin Wong; Leslie W. Chinn; Vaze; Jun Sonoda; Tom Gelzleichter; Shan Chen; Nicholas Lewin-Koh; Linda Morrow; Suresh Dheerendra; Richard Boismenu; Johnny Gutierrez; Eric Wakshull; Maria E. Wilson; Puneet S. Arora
Osteopontin Links Myeloid Activation and Disease Progression in Systemic Sclerosis
Cell Reports Medicine,
Xia Gao; Jim Jia; Anna Guttman; Daryle DePianto; Katrina B. Morshead; Kai-Hui Sun; Nandhini Ramamoorthi; Jason A. Vander Heiden; Zora Modrusan; Paul J. Wolters; Angelika Jahreis; Joe Arron; Dinesh Khanna; Thiru Ramalingam
Using differential scanning calorimetry for the development of non-reduced capillary electrophoresis sodium dodecyl sulfate methods for monoclonal antibodies
Analytical Biochemistry, ISSN: 00032697
Patricia Molina; Arthur J. Schick; Leslie Welch; Thomas Niedringhaus; Gabriella del Hierro; Galahad Deperalta; Aaron Hieb
Frontiers in Immunology, ISSN: 16643224
Steve Hack; Zhu; Yulei Wang
Improving Prediction of Free Fatty Acid Particle Formation in Biopharmaceutical Drug Products: Incorporating Ester Distribution during Polysorbate 20 Degradation
Molecular Pharmaceutics,
Nidhi Doshi; Joelle Martin; Anthony Tomlinson
Eye, ISSN: 14765454 0950222X
Anthony Adamis; Christopher Brittain; Atul Dandekar; Jill Hopkins
Characterization of Tissue Distribution, Catabolism, and Elimination of an Anti-Staphylococcus aureus THIOMAB Antibody-Antibiotic Conjugate in Rats
Drug Metabolism and Disposition,
Hao Cai; Victor Yip; Violet Lee; Sylvia Wong; Ola Saad; Shuguang Ma; Nina Ljumanovic; S Cyrus Khojasteh; Amrita Kamath; Ben-Quan Shen
Annals of the Rheumatic Diseases, ISSN: 14682060 00034967
Frances Humby; Myles J. Lewis; Michael Townsend; Costantino Pitzalis
AAPS Journal, ISSN: 15507416
Arian Emami Riedmaier; Kevin DeMent; James Huckle; Phil Bransford; Cordula Stillhart; Richard Lloyd; Ravindra Alluri; Sumit Basu; Yuan Chen; Varsha Dhamankar; Stephanie Dodd; Priyanka Kulkarni; Andrés Olivares-Morales; Chi-Chi Peng; Xavier Pepin; Xiaojun Ren; Thuy Tran; Christophe Tistaert; Tycho Heimbach; Filippos Kesisoglou; Christian Wagner; Neil Parrott
Comparison of techniques to control ice nucleation during lyophilization
Processes,
Jake Luoma; Erika Ingham; Carmen Lema Martinez; Andrea Allmendinger
Impact of Silicone Oil on Free Fatty Acid Particle Formation due to Polysorbate 20 Degradation
Pharmaceutical Research, ISSN: 07248741
Raphael Fish; Jasper Lin; Nidhi Doshi
Water related impact of energy: Cost and carbon footprint analysis of water for biopharmaceuticals from tap to waste
Chemical Engineering Science: X,
Alessandro Luigi Cataldo; Bernhard Sissolak; Karl Metzger; Kristi Budzinski; Osamu Shirokizawa; Markus Luchner; Alois Jungbauer; Peter Satzer
Nature, ISSN: 14764687 00280836
Erik L. Bao; Satish K. Nandakumar; Xiaotian Liao; Alexander G. Bick; Juha Karjalainen; Marcin Tabaka; Olga I. Gan; Aki S. Havulinna; Tuomo T. J. Kiiskinen; Caleb A. Lareau; Aitzkoa L. de Lapuente Portilla; Bo Li; Connor Emdin; Veryan Codd; Christopher P. Nelson; Christopher J. Walker; Claire Churchhouse; Albert de la Chapelle; Daryl E. Klein; Bj?rn Nilsson; Peter W. F. Wilson; Kelly Cho; Saiju Pyarajan; J. Michael Gaziano; Nilesh J. Samani; Aarno Palotie; Mark Daly; Howard Jacob; Heiko Runz; Sally John; Robert M. Plenge; Mark McCarthy; Dawn Waterworth; Caroline Fox; Anders Malarstig; Kathy Klinger; Kathy Call; Tomi P. M?kel?; Jaakko Kaprio; Petri Virolainen; Kari Pulkki; Terhi Kilpi; Markus Perola; Jukka Partanen; Anne Pitk?ranta; Riitta Kaarteenaho; Seppo Vainio; Veli-Matti Kosma; Urho Kujala; Jeff Waring; Heiko Runz; Jimmy Liu; Shameek Biswas; Dawn Waterworth; Meg Ehm; Caroline S. Fox; Anders M?larstig; Catherine Marshall; Xinli Hu; Kathy Call; Kathy Klinger; Matthias Gossel; Samuli Ripatti; Johanna Sc
Frontiers in Immunology, ISSN: 16643224
Sébastien Wieckowski; Cécile Avenal; Arturo Orjalo; Daniel Gygax; Florian Cymer
Journal of Medicinal Chemistry, ISSN: 15204804 00222623
Emily Hanan; Jun Liang; Xiaojing Wang; Robert Blake; Nicole Blaquiere; Steven Staben
Biochemistry, ISSN: 15204995 00062960
Nicholas P. D. Liau; Avinashnarayan Venkatanarayan; John Quinn; Wilson Phung; Shiva Malek; Sarah Hymowitz; Jawahar Sudhamsu
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